Learn the facts about
Primary Immunodeficiency (PI)

Primary immunodeficiency, commonly referred to as PI (also PID, PIDD and primary immune deficiency), is an umbrella term used to describe a group of more than 200 disorders that can cause your immune system to not work like it should.1

People living with PI face unique challenges as they:

People with primary immunodeficiency are more likely to get infections

Are more likely to get infections

People with primary immunodeficiency take longer to recover from infections

Take longer to recover from infections

People with primary immunodeficiency have recurring infections

Have recurring infections

Explore the
Immune System

Find out how this complex network of organs, tissues, and cells protects people from infection.

Learn More

Understand the Different Types of PI

What's your type? People who have different types of PI will be susceptible to different types of diseases.

Learn More

Recognize the
Symptoms of PI

Frequent or hard-to-cure infections? Know the tell tale signs of a compromised immune system and recognize the symptoms of PI in children and adults.

Learn the Signs

Finding answers to FAQs

Discover answers to some of your most common questions about PI.

Read the FAQs