« Understanding Primary Immunodeficiency (PI)

Symptoms
of PI

Primary immunodeficiency (PI) causes children and adults to have infections that come back frequently or are unusually hard to treat.

What are the warning signs of PI in children?

If your child has two or more of the following warning signs, talk to a physician about the possible presence of an underlying PI disorder and a possible PI diagnosis.1

  1. Four or more new ear infections within one year
  2. Two or more serious sinus infections within one year
  3. Two or more months on antibiotics with little effect
  4. Two or more pneumonias within one year
  5. Failure of an infant to gain weight or grow normally
  6. Recurrent, deep skin or organ abscesses
  7. Persistent thrush in mouth or fungal infection on skin
  8. Need for intravenous antibiotics to clear infections
  9. Two or more deep-seated infections including septicemia
  10. A family history of PI
10 Warning Signs of PI for Children

10 Warning Signs of PI for Children

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What are the warning signs of PI in adults?

If you or someone you know has two or more of the following warning signs, talk to a physician about the possible presence of an underlying PI disorder and a possible PI diagnosis.2

  1. Two or more new ear infections within one year
  2. Two or more new sinus infections within one year, in the absence of allergy
  3. One pneumonia per year for more than one year
  4. Chronic diarrhea with weight loss
  5. Recurrent viral infections (colds, herpes, warts, condyloma)
  6. Recurrent need for intravenous antibiotics to clear infections
  7. Recurrent, deep abscesses of the skin or internal organs
  8. Persistent thrush or fungal infection on the skin or elsewhere
  9. Infection with normally harmless tuberculosis-like bacteria
  10. A family history of PI
10 Warning Signs of PI for Adults

10 Warning Signs of PI for Adults

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