There are a number of specific medical treatments that can help people diagnosed with primary immunodeficiencies (PI) reduce their risk of bacterial infections. One of the most common is immunoglobulin (IgG) replacement therapy.

IgG is an antibody that helps your body fight germs. It can be infused into a vein in your arm (sometimes called IVIG) or infused into the fatty tissues just below your skin (SubQ). IgG infusions temporarily replace infection-fighting antibodies that some people with PI are missing.

There are other treatments available for types of PI which don’t benefit from IgG infusion. Your doctor will help you decide which treatment is best for you.1

Questions to Ask Your Doctor
Download questions to ask your doctor about treatment and living with PI.
What’s Best for Me?
Find out about differences between IVIG and SubQ.
How IVIG Works
Learn about IVIG administration and possible side effects.
How SubQ Works
Find out how SubQ works, how it’s administered, and what side effects may occur.
  1. Blaese RM, Winkelstein J. Patient & Family Handbook for Primary Immunodeficiency Diseases. Towson, MD: Immune Deficiency Foundation; 2007.